Science fiction has served as a speculative vehicle for evaluating and understanding the world in which we live. It is a type of fiction that is deeply rooted in the mythology of man. Since the early beginnings of story telling, man has utilized speculative fiction to not only make sense of the world, but to hypothesize about the future based on the present. In this sense, science fiction can be said to represent a type of mythological narrative that serves as both cultural mirror and cultural teacher. It is a timeless cultural phenomenon that can be used as a valuable teaching tool across disciplines in order to inspire unbiased critical thinking and discussion about concepts in literature, science, and social science. This discussion explores the many ways in which science fiction can be utilized to develop or enhance any course in the sciences and social sciences and will include real course examples of each.